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Designing of kinase hinge binders: A medicinal chemistry perspective -  Sharma - 2022 - Chemical Biology & Drug Design - Wiley Online Library
Designing of kinase hinge binders: A medicinal chemistry perspective - Sharma - 2022 - Chemical Biology & Drug Design - Wiley Online Library

Figure 1 from In Silico Identification of a Novel Hinge-Binding Scaffold  for Kinase Inhibitor Discovery. | Semantic Scholar
Figure 1 from In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery. | Semantic Scholar

JAK Kinases in Health and Disease: An Update
JAK Kinases in Health and Disease: An Update

Discovery of a novel kinase hinge binder fragment by dynamic undocking -  RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/C9MD00519F
Discovery of a novel kinase hinge binder fragment by dynamic undocking - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/C9MD00519F

Discovery of a novel kinase hinge binder fragment by dynamic undocking -  RSC Medicinal Chemistry (RSC Publishing)
Discovery of a novel kinase hinge binder fragment by dynamic undocking - RSC Medicinal Chemistry (RSC Publishing)

Designing of kinase hinge binders: A medicinal chemistry perspective -  Sharma - 2022 - Chemical Biology & Drug Design - Wiley Online Library
Designing of kinase hinge binders: A medicinal chemistry perspective - Sharma - 2022 - Chemical Biology & Drug Design - Wiley Online Library

Hinge Binders Library - Enamine
Hinge Binders Library - Enamine

Targeting the DFG-in kinase conformation: a new trend emerging from a  patent analysis | Future Medicinal Chemistry
Targeting the DFG-in kinase conformation: a new trend emerging from a patent analysis | Future Medicinal Chemistry

Frontiers | Clinically Precedented Protein Kinases: Rationale for Their Use  in Neurodegenerative Disease
Frontiers | Clinically Precedented Protein Kinases: Rationale for Their Use in Neurodegenerative Disease

A) ATP binding site region and ATP interactions with the hinge... |  Download Scientific Diagram
A) ATP binding site region and ATP interactions with the hinge... | Download Scientific Diagram

Molecules | Free Full-Text | Molecular Recognition of FDA-Approved Small  Molecule Protein Kinase Drugs in Protein Kinases
Molecules | Free Full-Text | Molecular Recognition of FDA-Approved Small Molecule Protein Kinase Drugs in Protein Kinases

Hinge Binders Library - Enamine
Hinge Binders Library - Enamine

A computational protocol to evaluate the effects of protein mutants in the  kinase gatekeeper position on the binding of ATP substrate analogues | BMC  Research Notes | Full Text
A computational protocol to evaluate the effects of protein mutants in the kinase gatekeeper position on the binding of ATP substrate analogues | BMC Research Notes | Full Text

Kincore: a web resource for structural classification of protein kinases  and their inhibitors | bioRxiv
Kincore: a web resource for structural classification of protein kinases and their inhibitors | bioRxiv

Kinase Inhibitors: An Introduction
Kinase Inhibitors: An Introduction

Protein Kinase Inhibitors: Insights into Drug Design from Structure |  Science
Protein Kinase Inhibitors: Insights into Drug Design from Structure | Science

Knowledge Based Prediction of Ligand Binding Modes and Rational Inhibitor  Design for Kinase Drug Discovery | Journal of Medicinal Chemistry
Knowledge Based Prediction of Ligand Binding Modes and Rational Inhibitor Design for Kinase Drug Discovery | Journal of Medicinal Chemistry

Contact with kinase hinge region through a hydrogen bond donating and... |  Download Scientific Diagram
Contact with kinase hinge region through a hydrogen bond donating and... | Download Scientific Diagram

Kinase hinge binding scaffolds and their hydrogen bond patterns -  ScienceDirect
Kinase hinge binding scaffolds and their hydrogen bond patterns - ScienceDirect

Defining a new nomenclature for the structures of active and inactive  kinases | PNAS
Defining a new nomenclature for the structures of active and inactive kinases | PNAS

Left: Schematic presentation of the kinase family-wide conserved... |  Download Scientific Diagram
Left: Schematic presentation of the kinase family-wide conserved... | Download Scientific Diagram

Overview of Current Type I/II Kinase Inhibitors
Overview of Current Type I/II Kinase Inhibitors

Cancers | Free Full-Text | Three-Dimensional Interactions Analysis of the  Anticancer Target c-Src Kinase with Its Inhibitors
Cancers | Free Full-Text | Three-Dimensional Interactions Analysis of the Anticancer Target c-Src Kinase with Its Inhibitors

New insights into the structural dynamics of the kinase JNK3 | Scientific  Reports
New insights into the structural dynamics of the kinase JNK3 | Scientific Reports

How far are we in the rapid prediction of drug resistance caused by kinase  mutations? | bioRxiv
How far are we in the rapid prediction of drug resistance caused by kinase mutations? | bioRxiv